Scientists Uncover Trigger for Most Common Form of Intellectual Disability and Autism
2 posters
NewsFix :: Science :: General Science
Page 1 of 1
Scientists Uncover Trigger for Most Common Form of Intellectual Disability and Autism
A new study led by Weill Cornell Medical College scientists shows that the most common genetic form of mental retardation and autism occurs because of a mechanism that shuts off the gene associated with the disease. The findings, published today in Science, also show that a drug that blocks this silencing mechanism can prevent fragile X syndrome — suggesting similar therapy is possible for 20 other diseases that range from mental retardation to multisystem failure.
Fragile X syndrome occurs mostly in boys, causing intellectual disability as well as telltale physical, behavioral and emotional traits. While researchers have known for more than two decades that the culprit behind the disease is an unusual mutation characterized by the excess repetition of a particular segment of the genetic code, they weren't sure why the presence of a large number of these repetitions — 200 or more — sets the disease process in motion.
Using stem cells from donated human embryos that tested positive for fragile X syndrome, the scientists discovered that early on in fetal development, messenger RNA — a template for protein production — begins sticking itself onto the fragile X syndrome gene's DNA. This binding appears to gum up the gene, making it inactive and unable to produce a protein crucial to the transmission of signals between brain cells.
http://weill.cornell.edu/news/pr/2014/02/scientists-uncover-trigger-for-most-common-form-of-intellectual-disability-and-autism-finding-may-ex.html
Fragile X syndrome occurs mostly in boys, causing intellectual disability as well as telltale physical, behavioral and emotional traits. While researchers have known for more than two decades that the culprit behind the disease is an unusual mutation characterized by the excess repetition of a particular segment of the genetic code, they weren't sure why the presence of a large number of these repetitions — 200 or more — sets the disease process in motion.
Using stem cells from donated human embryos that tested positive for fragile X syndrome, the scientists discovered that early on in fetal development, messenger RNA — a template for protein production — begins sticking itself onto the fragile X syndrome gene's DNA. This binding appears to gum up the gene, making it inactive and unable to produce a protein crucial to the transmission of signals between brain cells.
http://weill.cornell.edu/news/pr/2014/02/scientists-uncover-trigger-for-most-common-form-of-intellectual-disability-and-autism-finding-may-ex.html
Guest- Guest
Re: Scientists Uncover Trigger for Most Common Form of Intellectual Disability and Autism
For Christ's sake! I'm trying to put up decent threads which hopefully interest people of intelligence. Why do you have to spoil every single thread by making it about you? You probably don't have ADHD, you clearly suffer from narcissism pure and simple.Beekeeper wrote: A COUPLE of weeks back, I remember eddie commenting to someone like Elizel and/or Ben on another thread on here ~ that she believes that I might have a mild form of ADHD !!!
AS IT HAS been noted before that many ADHD sufferers, especially those more "mild" variants -
are also prone to being well above average in their intelligence and creativity quotients ~
that amateur diagnosis is always certainly a possibility..
IF I were to be found to be suffering from ADHD at some future date, then I reckon there's more than an even chance that the "triggers" for such conditions would undoubtedly include the brainless and idiotic attacks against me and other innocents from the trolling R/W goons currently infesting
this site !
Guest- Guest
Re: Scientists Uncover Trigger for Most Common Form of Intellectual Disability and Autism
I don't remember saying that but I'd like to find the thread where I said it so I can read it again.
eddie- King of Beards. Keeper of the Whip. Top Chef. BEES!!!!!! Mushroom muncher. Spider aficionado!
- Posts : 43129
Join date : 2013-07-28
Age : 25
Location : England
Similar topics
» Prostate cancer set to become most common form of disease, with half of cases diagnosed late
» Dispelling common misconceptions about science and what scientists do
» On World Autism Day, Charles Montgomery Burns announced Autism Funding cuts
» Reason: Common sense, for the common good
» Palestinian Intellectual Praises Israeli Democracy:
» Dispelling common misconceptions about science and what scientists do
» On World Autism Day, Charles Montgomery Burns announced Autism Funding cuts
» Reason: Common sense, for the common good
» Palestinian Intellectual Praises Israeli Democracy:
NewsFix :: Science :: General Science
Page 1 of 1
Permissions in this forum:
You cannot reply to topics in this forum
Sat Mar 18, 2023 12:28 pm by Ben Reilly
» TOTAL MADNESS Great British Railway Journeys among shows flagged by counter terror scheme ‘for encouraging far-right sympathies
Wed Feb 22, 2023 5:14 pm by Tommy Monk
» Interesting COVID figures
Tue Feb 21, 2023 5:00 am by Tommy Monk
» HAPPY CHRISTMAS.
Sun Jan 01, 2023 7:33 pm by Tommy Monk
» The Fight Over Climate Change is Over (The Greenies Won!)
Thu Dec 15, 2022 3:59 pm by Tommy Monk
» Trump supporter murders wife, kills family dog, shoots daughter
Mon Dec 12, 2022 1:21 am by 'Wolfie
» Quill
Thu Oct 20, 2022 10:28 pm by Tommy Monk
» Algerian Woman under investigation for torture and murder of French girl, 12, whose body was found in plastic case in Paris
Thu Oct 20, 2022 10:04 pm by Tommy Monk
» Wind turbines cool down the Earth (edited with better video link)
Sun Oct 16, 2022 9:19 am by Ben Reilly
» Saying goodbye to our Queen.
Sun Sep 25, 2022 9:02 pm by Maddog
» PHEW.
Sat Sep 17, 2022 6:33 pm by Syl
» And here's some more enrichment...
Thu Sep 15, 2022 3:46 pm by Ben Reilly
» John F Kennedy Assassination
Thu Sep 15, 2022 3:40 pm by Ben Reilly
» Where is everyone lately...?
Thu Sep 15, 2022 3:33 pm by Ben Reilly
» London violence over the weekend...
Mon Sep 05, 2022 2:19 pm by Tommy Monk
» Why should anyone believe anything that Mo Farah says...!?
Wed Jul 13, 2022 1:44 am by Tommy Monk
» Liverpool Labour defends mayor role poll after turnout was only 3% and they say they will push ahead with the option that was least preferred!!!
Mon Jul 11, 2022 1:11 pm by Tommy Monk
» Labour leader Keir Stammer can't answer the simple question of whether a woman has a penis or not...
Mon Jul 11, 2022 3:58 am by Tommy Monk
» More evidence of remoaners still trying to overturn Brexit... and this is a conservative MP who should be drummed out of the party and out of parliament!
Sun Jul 10, 2022 10:50 pm by Tommy Monk
» R Kelly 30 years, Ghislaine Maxwell 20 years... but here in UK...
Fri Jul 08, 2022 5:31 pm by Original Quill