Immune discovery 'may treat all cancer'
3 posters
Page 1 of 1
Immune discovery 'may treat all cancer'
A newly-discovered part of our immune system could be harnessed to treat all cancers, say scientists.
The Cardiff University team discovered a method of killing prostate, breast, lung and other cancers in lab tests.
The findings, published in Nature Immunology, have not been tested in patients, but the researchers say they have "enormous potential".
Experts said that although the work was still at an early stage, it was very exciting.
What have they found?
Our immune system is our body's natural defence against infection, but it also attacks cancerous cells.
The scientists were looking for "unconventional" and previously undiscovered ways the immune system naturally attacks tumours.
What they found was a T-cell inside people's blood. This is an immune cell that can scan the body to assess whether there is a threat that needs to be eliminated.
The difference is this one could attack a wide range of cancers.
"There's a chance here to treat every patient," researcher Prof Andrew Sewell told the BBC.
He added: "Previously nobody believed this could be possible.
"It raises the prospect of a 'one-size-fits-all' cancer treatment, a single type of T-cell that could be capable of destroying many different types of cancers across the population."
How does it work?
T-cells have "receptors" on their surface that allow them to "see" at a chemical level.
The Cardiff team discovered a T-cell and its receptor that could find and kill a wide range of cancerous cells in the lab including lung, skin, blood, colon, breast, bone, prostate, ovarian, kidney and cervical cancer cells.
Crucially, it left normal tissues untouched.
Exactly how it does this is still being explored.
This particular T-cell receptor interacts with a molecule called MR1, which is on the surface of every cell in the human body.
It is thought MR1 is flagging the distorted metabolism going on inside a cancerous cell to the immune system.
"We are the first to describe a T-cell that finds MR1 in cancer cells - that hasn't been done before, this is the first of its kind," research fellow Garry Dolton told the BBC.
https://www.bbc.co.uk/news/health-51182451
The Cardiff University team discovered a method of killing prostate, breast, lung and other cancers in lab tests.
The findings, published in Nature Immunology, have not been tested in patients, but the researchers say they have "enormous potential".
Experts said that although the work was still at an early stage, it was very exciting.
What have they found?
Our immune system is our body's natural defence against infection, but it also attacks cancerous cells.
The scientists were looking for "unconventional" and previously undiscovered ways the immune system naturally attacks tumours.
What they found was a T-cell inside people's blood. This is an immune cell that can scan the body to assess whether there is a threat that needs to be eliminated.
The difference is this one could attack a wide range of cancers.
"There's a chance here to treat every patient," researcher Prof Andrew Sewell told the BBC.
He added: "Previously nobody believed this could be possible.
"It raises the prospect of a 'one-size-fits-all' cancer treatment, a single type of T-cell that could be capable of destroying many different types of cancers across the population."
How does it work?
T-cells have "receptors" on their surface that allow them to "see" at a chemical level.
The Cardiff team discovered a T-cell and its receptor that could find and kill a wide range of cancerous cells in the lab including lung, skin, blood, colon, breast, bone, prostate, ovarian, kidney and cervical cancer cells.
Crucially, it left normal tissues untouched.
Exactly how it does this is still being explored.
This particular T-cell receptor interacts with a molecule called MR1, which is on the surface of every cell in the human body.
It is thought MR1 is flagging the distorted metabolism going on inside a cancerous cell to the immune system.
"We are the first to describe a T-cell that finds MR1 in cancer cells - that hasn't been done before, this is the first of its kind," research fellow Garry Dolton told the BBC.
https://www.bbc.co.uk/news/health-51182451
Guest- Guest
Re: Immune discovery 'may treat all cancer'
I’ve always said the answers to all illnesses are to be found within our bodies.
Great news.
Great news.
eddie- King of Beards. Keeper of the Whip. Top Chef. BEES!!!!!! Mushroom muncher. Spider aficionado!
- Posts : 43129
Join date : 2013-07-28
Age : 25
Location : England
Re: Immune discovery 'may treat all cancer'
Wonderful news, I hope it turns out to what is envisaged.
Vintage- Forum Detective ????♀️
- Posts : 2948
Join date : 2013-08-02
Re: Immune discovery 'may treat all cancer'
This is a fantastic development.
Tommy Monk- Forum Detective ????♀️
- Posts : 26319
Join date : 2014-02-12
Similar topics
» Doctors successfully treat two babies with leukemia using gene-edited immune cells
» Harnessing the Immune System to Fight Cancer
» Monkeys genetically modified for healthier immune systems, metabolism
» Migraines could be an immune system disease, opening up new treatment paths
» Scientists create designer virus to kickstart immune system and kill cancer
» Harnessing the Immune System to Fight Cancer
» Monkeys genetically modified for healthier immune systems, metabolism
» Migraines could be an immune system disease, opening up new treatment paths
» Scientists create designer virus to kickstart immune system and kill cancer
Page 1 of 1
Permissions in this forum:
You cannot reply to topics in this forum
Sat Mar 18, 2023 12:28 pm by Ben Reilly
» TOTAL MADNESS Great British Railway Journeys among shows flagged by counter terror scheme ‘for encouraging far-right sympathies
Wed Feb 22, 2023 5:14 pm by Tommy Monk
» Interesting COVID figures
Tue Feb 21, 2023 5:00 am by Tommy Monk
» HAPPY CHRISTMAS.
Sun Jan 01, 2023 7:33 pm by Tommy Monk
» The Fight Over Climate Change is Over (The Greenies Won!)
Thu Dec 15, 2022 3:59 pm by Tommy Monk
» Trump supporter murders wife, kills family dog, shoots daughter
Mon Dec 12, 2022 1:21 am by 'Wolfie
» Quill
Thu Oct 20, 2022 10:28 pm by Tommy Monk
» Algerian Woman under investigation for torture and murder of French girl, 12, whose body was found in plastic case in Paris
Thu Oct 20, 2022 10:04 pm by Tommy Monk
» Wind turbines cool down the Earth (edited with better video link)
Sun Oct 16, 2022 9:19 am by Ben Reilly
» Saying goodbye to our Queen.
Sun Sep 25, 2022 9:02 pm by Maddog
» PHEW.
Sat Sep 17, 2022 6:33 pm by Syl
» And here's some more enrichment...
Thu Sep 15, 2022 3:46 pm by Ben Reilly
» John F Kennedy Assassination
Thu Sep 15, 2022 3:40 pm by Ben Reilly
» Where is everyone lately...?
Thu Sep 15, 2022 3:33 pm by Ben Reilly
» London violence over the weekend...
Mon Sep 05, 2022 2:19 pm by Tommy Monk
» Why should anyone believe anything that Mo Farah says...!?
Wed Jul 13, 2022 1:44 am by Tommy Monk
» Liverpool Labour defends mayor role poll after turnout was only 3% and they say they will push ahead with the option that was least preferred!!!
Mon Jul 11, 2022 1:11 pm by Tommy Monk
» Labour leader Keir Stammer can't answer the simple question of whether a woman has a penis or not...
Mon Jul 11, 2022 3:58 am by Tommy Monk
» More evidence of remoaners still trying to overturn Brexit... and this is a conservative MP who should be drummed out of the party and out of parliament!
Sun Jul 10, 2022 10:50 pm by Tommy Monk
» R Kelly 30 years, Ghislaine Maxwell 20 years... but here in UK...
Fri Jul 08, 2022 5:31 pm by Original Quill