African-American, Hispanic men less likely to get treatment for prostate cancer, even with high-risk disease

African-American, Hispanic men less likely to get treatment for prostate cancer, even with high-risk disease

African-American and Hispanic men in the United States are less likely to receive therapy for prostate cancer compared to Caucasian men -- even when they have more aggressive disease, according to new research from Roswell Park Cancer Institute and Vanderbilt University Medical Center. The study, senior authored by Willie Underwood, III, MD, MPH, MSci, of Roswell Park, has been published online ahead of print in the journal Urology.

"Despite their higher risk for more aggressive disease, African-American men and Hispanic men are less likely to receive treatment, and less treatment may play a significant role in increased rates of death from prostate cancer," says Dr. Underwood, the paper's senior author and Associate Professor in the Department of Urology at Roswell Park. "This research demonstrates a need for an action plan to address a racial disparity that has been known for more than 20 years."

The study was based on data for 327,641 men diagnosed with localized prostate cancer between 2004 and 2011, as reported to the national Surveillance, Epidemiology and End Results (SEER) Program. The researchers evaluated factors including race, age, treatment, Gleason score, marital status, year of diagnosis, D'Amico risk classification and whether or not the men received definitive treatment.

The researchers concluded that African-American men and Hispanic men were less likely to receive therapy compared to Caucasian and Asian-American men, even when they had high risk prostate cancers (Gleason score of 7 or higher). It is possible that many of these men had opted to defer treatment while continuing in the care of medical professionals, an approach known as watchful waiting or active surveillance.

They also analyzed the data using the D'Amico risk model, which calculates the risk of recurrence following localized treatment for prostate cancer. The analysis reveals that African-American men diagnosed within each category -- low-, intermediate- and high-risk disease -- had significantly lower odds of receiving definitive treatment. Hispanic men with intermediate- or high-risk disease also had lower odds of receiving treatment.

More: https://www.sciencedaily.com/releases/2016/10/161007221714.htm